Some puppies eliminate in their crate due to isolation distress or separation anxiety. If you hear your puppy whining, howling, or panting when you aren't in sight, this may be the case. You can also set up a camera to see how your dog reacts if you leave the room, or ask your neighbors if your dog is excessively vocal when you aren't home. If you suspect your puppy may be experiencing isolation distress or separation anxiety, contact a certified positive reinforcement trainer or veterinary behaviorist.